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What are the dangerous complications of dengue fever?

Dengue fever, also known as “breakbone fever,” is known for common symptoms such as fever, aches (around the eyes or joints), nausea, and more. But did you know that dengue may also develop into serious conditions that may require hospitalisation? Spotting symptoms of dengue and seeking medical attention early may save lives and speed up one’s recovery.

One of the most concerning complications of dengue fever is dengue hemorrhagic fever (DHF). DHF causes a sudden increase in blood vessel leakage, resulting in increased bleeding within the body. Dengue shock syndrome (DSS) is a more severe form of DHF where patients experience low blood pressure and bodily shock due to internal bleeding. DHF and DSS often require immediate medical intervention.1

Another complication arising from dengue fever is organ impairment. The virus may directly affect organs such as the liver or the heart,2 which may lead to severe conditions such as rapid liver failure, renal dysfunction, and/or weak heart muscles.These complications may lead to long term health consequences that greatly decrease one's quality of life.3

Occasionally, dengue may also affect the central nervous system. Although not common, people with dengue can sometimes suffer from complications such as brain inflammation, nerve and muscle issues, and eye nerve involvement.4 These conditions require close medical attention and follow-up. 

Pregnant women infected with dengue fever also face considerable risks. The virus may cross the placenta, resulting in complications such as miscarriage, stillbirth, or preterm
labor.5

If you are feeling unwell and suspect dengue fever, do not hesitate to seek help from a healthcare professional. It is crucial to spot dengue symptoms early and seek help immediately to prevent serious complications from developing. Consult your healthcare professional early if you have any concerns about dengue.

Reference
  1. Owais, Syed Muhammad, et al. "Unforeseen complications: a case of dengue shock syndrome presenting with multi-organ dysfunction in a subtropical region." Tropical Medicine and Health 51.1 (2023): 39.
  2. Póvoa, Tiago F., et al. "Peripheral organs of dengue fatal cases present strong pro-inflammatory response with participation of IFNgamma-, TNF-alpha-and RANTES-producing cells." PLoS One 11.12 (2016): e0168973.
  3. Lum, Lucy CS, et al. "Quality of life of dengue patients." American Journal of Tropical Medicine and Hygiene 78.6 (2008): 862-867.
  4. Carod-Artal, Francisco Javier, et al. "Neurological complications of dengue virus infection." The Lancet Neurology 12.9 (2013): 906-919.
  5. Chong, Vanessa, Jennifer Zi Ling Tan, and Valliammai Jayanthi Thirunavuk Arasoo. "Dengue in pregnancy: a southeast asian perspective." Tropical Medicine and Infectious Disease 8.2 (2023): 86.